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KMID : 0359919880070010199
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Korean Journal of Nephrology
1988 Volume.7 No. 1 p.199 ~ p.205
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Cyclosporin A Induced Remission of Steroid Resistent Nephrotic Syndrome Concomittent with IgA Nephropathy
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Abstract
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We report a case of an 8 year-old-girl with steroid resistant nephrotic syndrome with pathologic features of minimal- change disease and deposition of IgA in the mesangial regions. She was treated with corticosteroid for 4 weeks without an initial response, and then pulse therapy was tried without effect.
Cyclosporin A was then administered with corticosteroid for 6 months and remission was successfully induced.
We discussed the concomittent presence of both minimal lesion nephrotic syndrome and IgA nephropathy, and their possible pathogenesis including T-cell abnormalities are reviewed.
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